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Phosphoinositide 3-Kinase Activity Controls the Chemoattractant-mediated Activation and Adaptation of Adenylyl Cyclase

The binding of chemoattractants to cognate G protein-coupled receptors activates a variety of signaling cascades that provide spatial and temporal cues required for chemotaxis. When subjected to uniform stimulation, these responses are transient, showing an initial peak of activation followed by a p...

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Autors principals: Comer, Frank I., Parent, Carole A.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1345673/
https://ncbi.nlm.nih.gov/pubmed/16267269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-08-0781
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