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Phosphatase 2A Negatively Regulates Mitotic Exit in Saccharomyces cerevisiae

In budding yeast Saccharomyces cerevisiae, Cdc5 kinase is a component of mitotic exit network (MEN), which inactivates cyclin-dependent kinase (CDK) after chromosome segregation. cdc5-1 mutants arrest at telophase at the nonpermissive temperature due to the failure of CDK inactivation. To identify m...

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Main Authors: Wang, Yanchang, Ng, Tuen-Yung
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Cell Biology 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1345648/
https://ncbi.nlm.nih.gov/pubmed/16079183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-12-1109
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