Metallothionien 3 expression is frequently down-regulated in oesophageal squamous cell carcinoma by DNA methylation

BACKGROUND: Metallothionein 3 (MT3) inhibits growth in a variety of cell types. We measured MT3 gene expression by RT-PCR, and DNA methylation in the MT3 promoter by combined bisulphite restriction analysis, in four oesophageal cancer cell lines and the resected oesophagus from 64 patients with oeso...

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Autors principals: Smith, Eric, Drew, Paul A, Tian, Zi-Qing, De Young, Neville J, Liu, Jun-Feng, Mayne, George C, Ruszkiewicz, Andrew R, Watson, David I, Jamieson, Glyn G
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2005
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1343579/
https://ncbi.nlm.nih.gov/pubmed/16351731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-4-42
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