A balanced transcription between telomerase and the telomeric DNA-binding proteins TRF1, TRF2 and Pot1 in resting, activated, HTLV-1-transformed and Tax-expressing human T lymphocytes

BACKGROUND: The functional state of human telomeres is controlled by telomerase and by a protein complex named shelterin, including the telomeric DNA-binding proteins TRF1, TRF2 and Pot1 involved in telomere capping functions. The expression of hTERT, encoding the catalytic subunit of telomerase, pl...

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Main Authors: Escoffier, Emmanuelle, Rezza, Amélie, Roborel de Climens, Aude, Belleville, Aurélie, Gazzolo, Louis, Gilson, Eric, Duc Dodon, Madeleine
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2005
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1343578/
https://ncbi.nlm.nih.gov/pubmed/16354306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-2-77
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