The human XPC DNA repair gene: arrangement, splice site information content and influence of a single nucleotide polymorphism in a splice acceptor site on alternative splicing and function

XPC DNA repair gene mutations result in the cancer-prone disorder xeroderma pigmentosum. The XPC gene spans 33 kb and has 16 exons (82–882 bp) and 15 introns (0.08–5.4 kb). A 1.6 kb intron was found within exon 5. Sensitive real- time quantitative reverse transcription–polymerase chain reaction meth...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Khan, Sikandar G., Muniz-Medina, Vanessa, Shahlavi, Tala, Baker, Carl C., Inui, Hiroki, Ueda, Takahiro, Emmert, Steffen, Schneider, Thomas D., Kraemer, Kenneth H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2002
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC134237/
https://ncbi.nlm.nih.gov/pubmed/12177305
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky