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Molecular Ordering of the Initial Signaling Events of CD95

Binding of either ligand or agonistic antibodies to the death receptor CD95 (APO-1/Fas) induces the formation of the death-inducing signaling complex (DISC). We now show that signal initiation of CD95 in type I cells can be further separated into at least four distinct steps. (i) The first step is l...

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Detalhes bibliográficos
Main Authors: Algeciras-Schimnich, Alicia, Shen, Le, Barnhart, Bryan C., Murmann, Andrea E., Burkhardt, Janis K., Peter, Marcus E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC134211/
https://ncbi.nlm.nih.gov/pubmed/11739735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.1.207-220.2002
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