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Molecular Ordering of the Initial Signaling Events of CD95
Binding of either ligand or agonistic antibodies to the death receptor CD95 (APO-1/Fas) induces the formation of the death-inducing signaling complex (DISC). We now show that signal initiation of CD95 in type I cells can be further separated into at least four distinct steps. (i) The first step is l...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC134211/ https://ncbi.nlm.nih.gov/pubmed/11739735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.1.207-220.2002 |
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