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Defective Signaling in a Subpopulation of CD4(+) T Cells in the Absence of Ca(2+)/Calmodulin-Dependent Protein Kinase IV

Ca(2+)/calmodulin-dependent protein kinase IV-deficient (CaMKIV(−/−)) mice have been used to investigate the role of this enzyme in CD4(+) T cells. We identify a functional defect in a subpopulation of CD4(+) T cells, characterized by a cell surface marker profile usually found on memory phenotype C...

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Autors principals: Anderson, Kristin A., Means, Anthony R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC134209/
https://ncbi.nlm.nih.gov/pubmed/11739719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.1.23-29.2002
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