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Mot1 Associates with Transcriptionally Active Promoters and Inhibits Association of NC2 in Saccharomyces cerevisiae

Mot1 stably associates with the TATA-binding protein (TBP), and it can dissociate TBP from DNA in an ATP-dependent manner. Mot1 acts as a negative regulator of TBP function in vitro, but genome-wide transcriptional profiling suggests that Mot1 positively affects about 10% of yeast genes and negative...

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Udgivet i:Mol Cell Biol
Principais autores: Geisberg, Joseph V., Moqtaderi, Zarmik, Kuras, Laurent, Struhl, Kevin
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2002
Fag:
Transcriptional Regulation
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC134071/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12417716/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.23.8122-8134.2002
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