Purified Box C/D snoRNPs Are Able To Reproduce Site-Specific 2′-O-Methylation of Target RNA In Vitro

Small nucleolar RNAs (snoRNAs) are associated in ribonucleoprotein particles localized to the nucleolus (snoRNPs). Most of the members of the box C/D family function in directing site-specific 2′-O-methylation of substrate RNAs. Although the selection of the target nucleotide requires the antisense...

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Autores principales: Galardi, Silvia, Fatica, Alessandro, Bachi, Angela, Scaloni, Andrea, Presutti, Carlo, Bozzoni, Irene
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2002
Materias:
Gene Expression
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC134041/
https://ncbi.nlm.nih.gov/pubmed/12215523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.19.6663-6668.2002
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