Characterization of lpa(2) (Edg4) and lpa(1)/lpa(2) (Edg2/Edg4) Lysophosphatidic Acid Receptor Knockout Mice: Signaling Deficits without Obvious Phenotypic Abnormality Attributable to lpa(2)

Lysophosphatidic acid (LPA), a bioactive lipid produced by several cell types including postmitotic neurons and activated platelets, is thought to be involved in various biological processes, including brain development. Three cognate G protein-coupled receptors encoded by lpa(1)/lp(A1)/Edg-2/Gpcr26...

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Detalhes bibliográficos
Main Authors: Contos, James J. A., Ishii, Isao, Fukushima, Nobuyuki, Kingsbury, Marcy A., Ye, Xiaoqin, Kawamura, Shuji, Heller Brown, Joan, Chun, Jerold
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC134025/
https://ncbi.nlm.nih.gov/pubmed/12215548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.19.6921-6929.2002
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