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Suprabasal Desmoglein 3 Expression in the Epidermis of Transgenic Mice Results in Hyperproliferation and Abnormal Differentiation

The desmoglein 1 (Dsg1) and desmocollin 1 (Dsc1) isoforms of the desmosomal cadherins are expressed in the suprabasal layers of epidermis, whereas Dsg3 and Dsc3 are more strongly expressed basally. This differential expression may have a function in epidermal morphogenesis and/or may regulate the pr...

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Detalles Bibliográficos
Main Authors: Merritt, Anita J., Berika, Mohamed Y., Zhai, Wenwu, Kirk, Sarah E., Ji, Baijing, Hardman, Matthew J., Garrod, David R.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC133994/
https://ncbi.nlm.nih.gov/pubmed/12138195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.16.5846-5858.2002
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