Selective Interactions between Vertebrate Polycomb Homologs and the SUV39H1 Histone Lysine Methyltransferase Suggest that Histone H3-K9 Methylation Contributes to Chromosomal Targeting of Polycomb Group Proteins

Polycomb group (PcG) proteins form multimeric chromatin-associated protein complexes that are involved in heritable repression of gene activity. Two distinct human PcG complexes have been characterized. The EED/EZH2 PcG complex utilizes histone deacetylation to repress gene activity. The HPC/HPH PcG...

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Main Authors: Sewalt, Richard G. A. B., Lachner, Monika, Vargas, Mark, Hamer, Karien M., den Blaauwen, Jan L., Hendrix, Thijs, Melcher, Martin, Schweizer, Dieter, Jenuwein, Thomas, Otte, Arie P.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2002
Assuntos:
DNA Dynamics and Chromosome Structure
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC133945/
https://ncbi.nlm.nih.gov/pubmed/12101246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.15.5539-5553.2002
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