Two Ras Pathways in Fission Yeast Are Differentially Regulated by Two Ras Guanine Nucleotide Exchange Factors

How a given Ras prreotein coordinates multiple signaling inputs and outputs is a fundamental issue of signaling specificity. Schizosaccharomyces pombe contains one Ras, Ras1, that has two distinct outputs. Ras1 activates Scd1, a presumptive guanine nucleotide exchange factor (GEF) for Cdc42, to cont...

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Bibliographic Details
Main Authors: Papadaki, Piyi, Pizon, Véronique, Onken, Brian, Chang, Eric C.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Cell Growth and Development
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC133927/
https://ncbi.nlm.nih.gov/pubmed/12052869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.13.4598-4606.2002
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