A Conserved Domain of Schizosaccharomyces pombe dfp1(+) Is Uniquely Required for Chromosome Stability following Alkylation Damage during S Phase

The fission yeast Dbf4 homologue Dfp1 has a well-characterized role in regulating the initiation of DNA replication. Sequence analysis of Dfp1 homologues reveals three highly conserved regions, referred to as motifs N, M, and C. To determine the roles of these conserved regions in Dfp1 function, we...

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Bibliografiske detaljer
Main Authors: Fung, Amy D., Ou, Jiongwen, Bueler, Stephanie, Brown, Grant W.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2002
Fag:
DNA Dynamics and Chromosome Structure
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC133926/
https://ncbi.nlm.nih.gov/pubmed/12052858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.13.4477-4490.2002
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