Maleylacetoacetate Isomerase (MAAI/GSTZ)-Deficient Mice Reveal a Glutathione-Dependent Nonenzymatic Bypass in Tyrosine Catabolism

In mammals, the catabolic pathway of phenylalanine and tyrosine is found in liver (hepatocytes) and kidney (proximal tubular cells). There are well-described human diseases associated with deficiencies of all enzymes in this pathway except for maleylacetoacetate isomerase (MAAI), which converts male...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Fernández-Cañón, José Manuel, Baetscher, Manfred W., Finegold, Milton, Burlingame, Terry, Gibson, K. Michael, Grompe, Markus
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 2002
Soggetti:	Mammalian Genetic Models with Minimal or Complex Phenotypes
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133921/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12052898/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.13.4943-4951.2002
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