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Rad23 Promotes the Targeting of Proteolytic Substrates to the Proteasome

Rad23 contains a ubiquitin-like domain (UbL(R23)) that interacts with catalytically active proteasomes and two ubiquitin (Ub)-associated (UBA) sequences that bind Ub. The UBA domains can bind Ub in vitro, although the significance of this interaction in vivo is poorly understood. Rad23 can interfere...

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Détails bibliographiques
Auteurs principaux: Chen, Li, Madura, Kiran
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2002
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC133919/
https://ncbi.nlm.nih.gov/pubmed/12052895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.13.4902-4913.2002
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