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Retinoic Acid Receptors Inhibit AP1 Activation by Regulating Extracellular Signal-Regulated Kinase and CBP Recruitment to an AP1-Responsive Promoter

Retinoids exhibit antineoplastic activities that may be linked to retinoid receptor-mediated transrepression of activating protein 1 (AP1), a heterodimeric transcription factor composed of fos- and jun-related proteins. Here we show that transcriptional activation of an AP1-regulated gene through th...

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Autors principals: Benkoussa, Madjid, Brand, Céline, Delmotte, Marie-Hélène, Formstecher, Pierre, Lefebvre, Philippe
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC133906/
https://ncbi.nlm.nih.gov/pubmed/12052862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.13.4522-4534.2002
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