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Cyclin D and cdk4 Are Required for Normal Development beyond the Blastula Stage in Sea Urchin Embryos

cdk4 mRNA and protein are constitutively expressed in sea urchin eggs and throughout embryonic development. In contrast, cyclin D mRNA is barely detectable in eggs and early embryos, when the cell cycles consist of alternating S and M phases. Cyclin D mRNA increases dramatically in embryos at the ea...

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Detalles Bibliográficos
Main Authors: Moore, Jennifer C., Sumerel, Jan L., Schnackenberg, Bradley J., Nichols, Jason A., Wikramanayake, Athula, Wessel, Gary M., Marzluff, William F.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC133905/
https://ncbi.nlm.nih.gov/pubmed/12052892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.13.4863-4875.2002
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