Targeting Protein Phosphatase 1 (PP1) to the Actin Cytoskeleton: the Neurabin I/PP1 Complex Regulates Cell Morphology

Neurabin I, a neuronal actin-binding protein, binds protein phosphatase 1 (PP1) and p70 ribosomal S6 protein kinase (p70S6K), both proteins implicated in cytoskeletal dynamics. We expressed wild-type and mutant neurabins fused to green fluorescent protein in Cos7, HEK293, and hippocampal neurons. Bi...

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Autores principales: Oliver, Carey J., Terry-Lorenzo, Ryan T., Elliott, Elizabeth, Christensen Bloomer, Wendy A., Li, Shi, Brautigan, David L., Colbran, Roger J., Shenolikar, Shirish
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2002
Materias:
Cell Growth and Development
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC133892/
https://ncbi.nlm.nih.gov/pubmed/12052877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.13.4690-4701.2002
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