Proteasomal Inhibition Enhances Glucocorticoid Receptor Transactivation and Alters Its Subnuclear Trafficking

The ubiquitin-proteasome pathway regulates the turnover of many transcription factors, including steroid hormone receptors such as the estrogen receptor and progesterone receptor. For these receptors, proteasome inhibition interferes with steroid-mediated transcription. We show here that proteasome...

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Bibliographische Detailangaben
Hauptverfasser: Deroo, Bonnie J., Rentsch, Claudia, Sampath, Sowmini, Young, Janel, DeFranco, Donald B., Archer, Trevor K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2002
Schlagworte:
Transcriptional Regulation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC133869/
https://ncbi.nlm.nih.gov/pubmed/12024025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.12.4113-4123.2002
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