The DNA Architectural Protein HMGB1 Displays Two Distinct Modes of Action That Promote Enhanceosome Assembly

HMGB1 (also called HMG-1) is a DNA-bending protein that augments the affinity of diverse regulatory proteins for their DNA sites. Previous studies have argued for a specific interaction between HMGB1 and target proteins, which leads to cooperative binding of the complex to DNA. Here we propose a dif...

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Bibliografiske detaljer
Main Authors: Mitsouras, Katherine, Wong, Ben, Arayata, Charina, Johnson, Reid C., Carey, Michael
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2002
Fag:
Transcriptional Regulation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC133865/
https://ncbi.nlm.nih.gov/pubmed/12024049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.12.4390-4401.2002
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