Mitochondrial NAD-Dependent Methylenetetrahydrofolate Dehydrogenase-Methenyltetrahydrofolate Cyclohydrolase Is Essential for Embryonic Development

Folate-dependent enzymes are compartmentalized between the cytoplasm and mitochondria of eukaryotes. The role of mitochondrial folate-dependent metabolism and the extent of its contribution to cytoplasmic processes are areas of active investigation. NAD-dependent methylenetetrahydrofolate dehydrogen...

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Bibliografiske detaljer
Main Authors: Di Pietro, E., Sirois, J., Tremblay, M. L., MacKenzie, R. E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2002
Fag:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC133862/
https://ncbi.nlm.nih.gov/pubmed/12024029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.12.4158-4166.2002
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