Activation of Ras and the Mitogen-Activated Protein Kinase Pathway Promotes Protein Degradation in Muscle Cells of Caenorhabditis elegans

To discover and study intracellular signals that regulate proteolysis in muscle, we have employed transgenic strains of Caenorhabditis elegans that produce a soluble LacZ reporter protein limited to body-wall and vulval muscles. This reporter protein is stable in well-fed wild-type animals, but its...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Szewczyk, Nathaniel J., Peterson, Brant K., Jacobson, Lewis A.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 2002
Soggetti:	Cell Growth and Development
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133852/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12024031/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.12.4181-4188.2002
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