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Role of SHP-2 in Fibroblast Growth Factor Receptor-Mediated Suppression of Myogenesis in C2C12 Myoblasts

Ligand activation of the fibroblast growth factor receptor (FGFR) represses myogenesis and promotes activation of extracellular signal-regulated kinases 1 and 2 (Erks). The precise mechanism through which the FGFR transmits both of these signals in myoblasts remains unclear. The SH2 domain-containin...

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Detalhes bibliográficos
Main Authors: Kontaridis, Maria I., Liu, Xiangdong, Zhang, Lei, Bennett, Anton M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC133814/
https://ncbi.nlm.nih.gov/pubmed/11997521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.11.3875-3891.2002
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