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c-Abl Tyrosine Kinase Regulates the Human Rad9 Checkpoint Protein in Response to DNA Damage

The ubiquitously expressed c-Abl tyrosine kinase is activated in the apoptotic response of cells to DNA damage. The mechanisms by which c-Abl signals the induction of apoptosis are not understood. Here we show that c-Abl binds constitutively to the mammalian homolog of the Schizosaccharomyces pombe...

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Udgivet i:Mol Cell Biol
Principais autores: Yoshida, Kiyotsugu, Komatsu, Kiyoshi, Wang, Hong-Gang, Kufe, Donald
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2002
Fag:
Cell Growth and Development
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133797/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11971963/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.10.3292-3300.2002
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