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The Mnd1 Protein Forms a Complex with Hop2 To Promote Homologous Chromosome Pairing and Meiotic Double-Strand Break Repair

The hop2 mutant of Saccharomyces cerevisiae arrests in meiosis with extensive synaptonemal complex (SC) formation between nonhomologous chromosomes. A screen for multicopy suppressors of a hop2-ts allele identified the MND1 gene. The mnd1-null mutant arrests in meiotic prophase, with most double-str...

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Main Authors: Tsubouchi, Hideo, Roeder, G. Shirleen
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC133769/
https://ncbi.nlm.nih.gov/pubmed/11940665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.9.3078-3088.2002
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