Evidence that Negative Elongation Factor Represses Transcription Elongation through Binding to a DRB Sensitivity-Inducing Factor/RNA Polymerase II Complex and RNA

Negative elongation factor (NELF) is a human transcription factor complex that cooperates with DRB sensitivity-inducing factor (DSIF)/hSpt4-hSpt5 to repress elongation by RNA polymerase II (RNAPII). NELF activity is associated with five polypeptides, including NELF-A, a candidate gene product for Wo...

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Bibliographic Details
Main Authors: Yamaguchi, Yuki, Inukai, Naoto, Narita, Takashi, Wada, Tadashi, Handa, Hiroshi
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Transcriptional Regulation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC133766/
https://ncbi.nlm.nih.gov/pubmed/11940650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.9.2918-2927.2002
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