Conserved Furin Cleavage Site Not Essential for Secretion and Integration of ZP3 into the Extracellular Egg Coat of Transgenic Mice

The extracellular zona pellucida surrounding mammalian eggs is formed by interactions of the ZP1, ZP2, and ZP3 glycoproteins. Female mice lacking ZP2 or ZP3 do not form a stable zona matrix and are sterile. The three zona proteins are synthesized in growing oocytes and secreted prior to incorporatio...

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Detalhes bibliográficos
Main Authors: Zhao, Ming, Gold, Lyn, Ginsberg, Ann M., Liang, Li-Fang, Dean, Jurrien
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC133755/
https://ncbi.nlm.nih.gov/pubmed/11940668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.9.3111-3120.2002
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