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Structural Insight into the Mechanisms of Targeting and Signaling of Focal Adhesion Kinase
Focal adhesion kinase (FAK) is a nonreceptor tyrosine kinase whose focal adhesion targeting (FAT) domain interacts with other focal adhesion molecules in integrin-mediated signaling. Localization of activated FAK to focal adhesions is indispensable for its function. Here we describe a solution struc...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2002
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC133741/ https://ncbi.nlm.nih.gov/pubmed/11909967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.8.2751-2760.2002 |
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