Hydrocephalus, Situs Inversus, Chronic Sinusitis, and Male Infertility in DNA Polymerase λ-Deficient Mice: Possible Implication for the Pathogenesis of Immotile Cilia Syndrome

A growing number of DNA polymerases have been identified, although their physiological function and relation to human disease remain mostly unknown. DNA polymerase λ (Pol λ; also known as Pol β2) has recently been identified as a member of the X family of DNA polymerases and shares 32% amino acid se...

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Autores principales: Kobayashi, Yosuke, Watanabe, Miho, Okada, Yuki, Sawa, Hirofumi, Takai, Hiroyuki, Nakanishi, Makoto, Kawase, Yosuke, Suzuki, Hiroshi, Nagashima, Kazuo, Ikeda, Kyoji, Motoyama, Noboru
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2002
Materias:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC133740/
https://ncbi.nlm.nih.gov/pubmed/11909969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.8.2769-2776.2002
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