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Enhanced Endotoxin Sensitivity in Fps/Fes-Null Mice with Minimal Defects in Hematopoietic Homeostasis

The fps/fes proto-oncogene encodes a cytoplasmic protein tyrosine kinase implicated in growth factor and cytokine receptor signaling and thought to be essential for the survival and terminal differentiation of myeloid progenitors. Fps/Fes-null mice were healthy and fertile, displayed slightly reduce...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zirngibl, Ralph A., Senis, Yotis, Greer, Peter A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC133716/
https://ncbi.nlm.nih.gov/pubmed/11909942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.8.2472-2486.2002
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