Targeted Disruption of the Testicular SPAG5/Deepest Protein Does Not Affect Spermatogenesis or Fertility

In an effort to define the molecular basis for morphogenesis of major sperm tail structures, including outer dense fibers, we recently cloned the Spag5 gene by virtue of its strong and specific leucine-zipper-mediated interaction with Odf1, the 27-kDa major outer dense fiber protein. Spag5 is expres...

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Autori principali: Xue, Jiaping, Tarnasky, Heide A., Rancourt, Derrick E., van der Hoorn, Frans A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2002
Soggetti:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC133686/
https://ncbi.nlm.nih.gov/pubmed/11884588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.7.1993-1997.2002
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