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Essential Regions of Saccharomyces cerevisiae Telomerase RNA: Separate Elements for Est1p and Est2p Interaction

The Saccharomyces cerevisiae telomerase RNA subunit is encoded by the TLC1 gene. A selection for viable alleles of TLC1 RNA from a large library of random deletion alleles revealed that less than half (∼0.5 kb of the ∼1.3-kb RNA) is required for telomerase function in vivo. The main essential region...

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Main Authors: Livengood, April J., Zaug, Arthur J., Cech, Thomas R.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2002
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC133682/
https://ncbi.nlm.nih.gov/pubmed/11884619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.7.2366-2374.2002
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