The Ubiquitin Ligase Component Siah1a Is Required for Completion of Meiosis I in Male Mice

The mammalian Siah genes encode highly conserved proteins containing a RING domain. As components of E3 ubiquitin ligase complexes, Siah proteins facilitate the ubiquitination and degradation of diverse protein partners including β-catenin, N-CoR, and DCC. We used gene targeting in mice to analyze t...

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Bibliographische Detailangaben
Hauptverfasser: Dickins, Ross A., Frew, Ian J., House, Colin M., O'Bryan, Moira K., Holloway, Andrew J., Haviv, Izhak, Traficante, Nadia, de Kretser, David M., Bowtell, David D. L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2002
Schlagworte:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC133675/
https://ncbi.nlm.nih.gov/pubmed/11884614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.7.2294-2303.2002
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