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Phospholipase D2 Is Localized to the Rims of the Golgi Apparatus in Mammalian Cells

Phospholipase D (PLD) hydrolyzes phosphatidylcholine to generate phosphatidic acid, a molecule known to have multiple physiological roles, including release of nascent secretory vesicles from the trans-Golgi network. In mammalian cells two forms of the enzyme, PLD1 and PLD2, have been described. We...

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Autori principali: Freyberg, Zachary, Bourgoin, Sylvain, Shields, Dennis
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC133604/
https://ncbi.nlm.nih.gov/pubmed/12429836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.02-04-0059
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