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The Intracellular pH-regulatory HCO(3)(−)/Cl(−) Exchanger in the Mouse Oocyte Is Inactivated during First Meiotic Metaphase and Reactivated after Egg Activation via the MAP Kinase Pathway
The HCO(3)(−)/Cl(−) exchanger is quiescent in the unfertilized mouse egg but is highly active in regulating intracellular pH in the early embryo and required for normal development. We show here that the HCO(3)(−)/Cl(−) exchanger is active in first meiotic prophase (GV) oocyte but inactivated during...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC133593/ https://ncbi.nlm.nih.gov/pubmed/12429825 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-04-0242 |
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