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Role of the Sin3-Histone Deacetylase Complex in Growth Regulation by the Candidate Tumor Suppressor p33(ING1)

Sin3 is an evolutionarily conserved corepressor that exists in different complexes with the histone deacetylases HDAC1 and HDAC2. Sin3-HDAC complexes are believed to deacetylate nucleosomes in the vicinity of Sin3-regulated promoters, resulting in a repressed chromatin structure. We have previously...

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Detalles Bibliográficos
Autores principales: Kuzmichev, A., Zhang, Y., Erdjument-Bromage, H., Tempst, P., Reinberg, D.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2002
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC133546/
https://ncbi.nlm.nih.gov/pubmed/11784859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.3.835-848.2002
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