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Direct Activation of Mitogen-Activated Protein Kinase Kinase Kinase MEKK1 by the Ste20p Homologue GCK and the Adapter Protein TRAF2

Mitogen-activated protein kinase (MAPK) pathways coordinate critical cellular responses to mitogens, stresses, and developmental cues. The coupling of MAPK kinase kinase (MAP3K) → MAPK kinase (MEK) → MAPK core pathways to cell surface receptors remains poorly understood. Recombinant forms of MAP3K M...

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Detalhes bibliográficos
Main Authors: Chadee, Deborah N., Yuasa, Takashi, Kyriakis, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC133545/
https://ncbi.nlm.nih.gov/pubmed/11784851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.3.737-749.2002
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