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Mammalian αI-spectrin is a neofunctionalized polypeptide adapted to small highly deformable erythrocytes

Mammalian red blood cells, unlike those of other vertebrates, must withstand the rigors of circulation in the absence of new protein synthesis. Key to this is plasma membrane elasticity deriving from the protein spectrin, which forms a network on the cytoplasmic face. Spectrin is a tetramer (αβ)(2),...

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Autori principali: Salomao, Marcela, An, Xiuli, Guo, Xinhua, Gratzer, Walter B., Mohandas, Narla, Baines, Anthony J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1334653/
https://ncbi.nlm.nih.gov/pubmed/16407147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0507661103
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