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Mammalian αI-spectrin is a neofunctionalized polypeptide adapted to small highly deformable erythrocytes

Mammalian red blood cells, unlike those of other vertebrates, must withstand the rigors of circulation in the absence of new protein synthesis. Key to this is plasma membrane elasticity deriving from the protein spectrin, which forms a network on the cytoplasmic face. Spectrin is a tetramer (αβ)(2),...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Salomao, Marcela, An, Xiuli, Guo, Xinhua, Gratzer, Walter B., Mohandas, Narla, Baines, Anthony J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1334653/
https://ncbi.nlm.nih.gov/pubmed/16407147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0507661103
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