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Mammalian αI-spectrin is a neofunctionalized polypeptide adapted to small highly deformable erythrocytes

Mammalian red blood cells, unlike those of other vertebrates, must withstand the rigors of circulation in the absence of new protein synthesis. Key to this is plasma membrane elasticity deriving from the protein spectrin, which forms a network on the cytoplasmic face. Spectrin is a tetramer (αβ)(2),...

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Autors principals: Salomao, Marcela, An, Xiuli, Guo, Xinhua, Gratzer, Walter B., Mohandas, Narla, Baines, Anthony J.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1334653/
https://ncbi.nlm.nih.gov/pubmed/16407147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0507661103
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