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The peptidoglycan recognition protein PGRP-SC1a is essential for Toll signaling and phagocytosis of Staphylococcus aureus in Drosophila

From a forward genetic screen for phagocytosis mutants in Drosophila melanogaster, we identified a mutation that affects peptidoglycan recognition protein (PGRP) SC1a and impairs the ability to phagocytose the bacteria Staphylococcus aureus, but not Escherichia coli and Bacillus subtilis. Because of...

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Autors principals: Garver, Lindsey S., Wu, Junlin, Wu, Louisa P.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1334640/
https://ncbi.nlm.nih.gov/pubmed/16407137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506182103
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