Allosteric changes of the NMDA receptor trap diffusible dopamine 1 receptors in spines

The dopaminergic and glutamatergic systems interact to initiate and organize normal behavior, a communication that may be perturbed in many neuropsychiatric diseases, including schizophrenia. We show here that NMDA, by allosterically modifying NMDA receptors, can act as a scaffold to recruit lateral...

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Autors principals: Scott, Lena, Zelenin, Sergey, Malmersjö, Seth, Kowalewski, Jacob M., Markus, Eivor Zettergren, Nairn, Angus C., Greengard, Paul, Brismar, Hjalmar, Aperia, Anita
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2006
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1334633/
https://ncbi.nlm.nih.gov/pubmed/16407151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0505557103
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