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Structural analysis of adenylate cyclases from Trypanosoma brucei in their monomeric state
Cyclic AMP is a major trigger of the differentiation process of Trypanosoma brucei, a bloodstream parasite causing sleeping sickness. Its generation in trypanosomes is accomplished by a unique battery of membrane-bound adenylate cyclases (ACs). We have determined the high-resolution X-ray structures...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2001
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC133460/ https://ncbi.nlm.nih.gov/pubmed/11157750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.3.433 |
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