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Structural analysis of adenylate cyclases from Trypanosoma brucei in their monomeric state

Cyclic AMP is a major trigger of the differentiation process of Trypanosoma brucei, a bloodstream parasite causing sleeping sickness. Its generation in trypanosomes is accomplished by a unique battery of membrane-bound adenylate cyclases (ACs). We have determined the high-resolution X-ray structures...

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Detalhes bibliográficos
Main Authors: Bieger, Boris, Essen, Lars-Oliver
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC133460/
https://ncbi.nlm.nih.gov/pubmed/11157750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.3.433
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