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Genomic functional annotation using co-evolution profiles of gene clusters

BACKGROUND: The current speed of sequencing already exceeds the capability of annotation, creating a potential bottleneck. A large proportion of the genes in microbial genomes remains uncharacterized. Here we propose a new method for functional annotation using the conservation patterns of gene clus...

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Detalles Bibliográficos
Autores principales: Zheng, Yu, Roberts, Richard J, Kasif, Simon
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2002
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC133444/
https://ncbi.nlm.nih.gov/pubmed/12429059
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