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Effects of mesolimbic dopamine depletion on responding maintained by cocaine and food.

The hypothesis that mesolimbic dopamine is selectively involved in cocaine reinforcement was investigated in the rat. Animals were trained under a multiple schedule in which responding was reinforced by intravenous cocaine (0.75 mg/kg/injection) or food (45-mg pellets) under fixed-ratio 15 schedule...

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Détails bibliographiques
Auteurs principaux: Caine, S B, Koob, G F
Format: Artigo
Langue:Inglês
Publié: 1994
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1334409/
https://ncbi.nlm.nih.gov/pubmed/8169570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1901/jeab.1994.61-213
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