Gene Expression Programs in Response to Hypoxia: Cell Type Specificity and Prognostic Significance in Human Cancers

BACKGROUND: Inadequate oxygen (hypoxia) triggers a multifaceted cellular response that has important roles in normal physiology and in many human diseases. A transcription factor, hypoxia-inducible factor (HIF), plays a central role in the hypoxia response; its activity is regulated by the oxygen-de...

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Main Authors: Chi, Jen-Tsan, Wang, Zhen, Nuyten, Dimitry S. A, Rodriguez, Edwin H, Schaner, Marci E, Salim, Ali, Wang, Yun, Kristensen, Gunnar B, Helland, Åslaug, Børresen-Dale, Anne-Lise, Giaccia, Amato, Longaker, Michael T, Hastie, Trevor, Yang, George P, van de Vijver, Marc J, Brown, Patrick O
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2006
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1334226/
https://ncbi.nlm.nih.gov/pubmed/16417408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0030047
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