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Saccharomyces cerevisiae Est3p dimerizes in vitro and dimerization contributes to efficient telomere replication in vivo

In Saccharomyces cerevisiae at least five genes, EST1, EST2, EST3, TLC1 and CDC13, are required for telomerase activity in vivo. The telomerase catalytic subunit Est2p and telomerase RNA subunit Tlc1 constitute the telomerase core enzyme. Est1p and Est3p are the other subunits of telomerase holoenzy...

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Sonraí Bibleagrafaíochta
Main Authors: Yang, Cui-Ping, Chen, Yong-Bin, Meng, Fei-Long, Zhou, Jin-Qiu
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2006
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1331985/
https://ncbi.nlm.nih.gov/pubmed/16418502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkj445
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