Genetic Analysis of Completely Sequenced Disease-Associated MHC Haplotypes Identifies Shuffling of Segments in Recent Human History

The major histocompatibility complex (MHC) is recognised as one of the most important genetic regions in relation to common human disease. Advancement in identification of MHC genes that confer susceptibility to disease requires greater knowledge of sequence variation across the complex. Highly dupl...

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Main Authors: Traherne, James A, Horton, Roger, Roberts, Anne N, Miretti, Marcos M, Hurles, Matthew E, Stewart, C. Andrew, Ashurst, Jennifer L, Atrazhev, Alexey M, Coggill, Penny, Palmer, Sophie, Almeida, Jeff, Sims, Sarah, Wilming, Laurens G, Rogers, Jane, de Jong, Pieter J., Carrington, Mary, Elliott, John F, Sawcer, Stephen, Todd, John A, Trowsdale, John, Beck, Stephan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1331980/
https://ncbi.nlm.nih.gov/pubmed/16440057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0020009
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