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The mechanism of excitation by acetylcholine in the cerebral cortex

1. The muscarinic depolarizing action of ACh on cortical neurones is associated with an increase in membrane resistance (mean ΔV/ΔR = 3·16 mV/MΩ). 2. ACh also promotes repetitive firing by slowing repolarization after spikes. 3. The depolarizing effect has a mean reversal level of -86·7 mV (with mea...

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Autori principali: Krnjević, K., Pumain, R., Renaud, L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1971
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1331876/
https://ncbi.nlm.nih.gov/pubmed/5579661
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